This edition comprises articles that were presented at the 4th International Seminar on Fundamental and Application of Chemical Engineering (ISFAChE 2022, Surabaya, Indonesia, October 26-27, 2022, Indonesia, online). Articles showcase the latest research findings in the field of chemical engineering, biotechnologies, bio-based materials and technologies of biofuel production, waste recycling, wastewater treatment and energy storage. The publication will be relevant to many specialists of various profiles.